The Board of Trustees of the Leland Stanford Junior University;Circuit Therapeutics, Inc.
发明人:
Karl A. Deisseroth,Elizabeth R. Aden,Viviana Gradinaru,Scott L. Delp
申请号:
US14921929
公开号:
US20160038761A1
申请日:
2015.10.23
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Provided herein are methods for the treatment of bladder dysfunction, including detrusor hyperreflexia and detrusor external sphincter dyssynergia, fecal incontinence, and/or sexual dysfunction in an individual via the use of stably expressed light-responsive opsin proteins capable of selective hyperpolarization or depolarization of the neural cells that innervate the muscles responsible for physiologic functioning of urinary bladder, external urinary sphincter, external anal sphincter, and the male and female genitalia.