CIRCUIT THERAPEUTICS, INC.;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
DEISSEROTH, KARL A.,ADEN, ELIZABETH R.,GRADINARU, VIVIANA,DELP, SCOTT L.
申请号:
EP13751108
公开号:
EP2817068A4
申请日:
2013.02.21
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Provided herein are methods for the treatment of bladder dysfunction, including detrusor hyperreflexia and detrusor external sphincter dyssynergia, fecal incontinence, and/or sexual dysfunction in an individual via the use of stably expressed light-responsive opsin proteins capable of selective hyperpolarization or depolarization of the neural cells that innervate the muscles responsible for physiologic functioning of urinary bladder, external urinary sphincter, external anal sphincter, and the male and female genitalia.