KASU RAGHU RAMI REDDY,DAS SUBHASIS,THOMMANDRU VIJAYA KUMAR
申请号：
IN2527/MUMNP/2012
公开号：
IN2012MN02527A
申请日:
2012.11.06
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The present invention relates to controlled release pharmaceutical compositions comprising Brivaracetam or its pharmaceutically acceptable derivatives thereof. Further disclosed is a controlled release pharmaceutical composition comprising a core and a coating surrounding the core wherein the core comprises Brivaracetam or pharmaceutically acceptable derivative thereof and the coating comprises hydrophobic release controlling agent. The controlled release pharmaceutical composition comprises Brivaracetam or pharmaceutically acceptable derivatives thereof and hydrophobic release controlling agent wherein said composition has dissolution of Brivaracetam at least 80 % between about 7 to about 24 hours when measured in 900 ml of pH 6 phosphate buffer solution using USP apparatus type II at 50 rpm and at 37°C. Also disclosed is a controlled release pharmaceutical composition useful for the treatment of epilepsy and treatment of symptomatic myoclonus comprises Brivaracetam or pharmaceutically acceptable derivative thereof and hydrophobic release controlling agent.
