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ASYMMETRICALLY COATED TABLET
专利权人:
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
发明人:
KIM, CHERNG-JU
申请号:
EP06771637
公开号:
EP1912629A4
申请日:
2006.05.30
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The medicament of tablet (10) release. The form of tablet (10) be asymmetric coated tablet to release immediately or delayed release time can accurately control with above-mentioned extended release plate 0 can sequence or single order extended release and pulse release depend on excipient tablet formulation used. The tablet (10) of core (11) is coated with asymmetrical coating, i.e. coating has different property from region (14,15). The coating may include drug in various concentration. In addition, the coating in different regions (14,15) can have different rate of dissolutions. The piece (10) of core (11) has the tablet of constant cross-sectional area (12) length along longitudinal direction, and coating has first area (14) with faster solution rate than second area (15). Dissolution only exposes the cross-sectional area (12) and dissolution medium of first area (14). The coating of second area (15) prevents the tablet of any other part core (11) to be not exposed to dissolving medium. Therefore, because sectional area (12) remains unchanged, actually dissolve, the rate of release of drug is kept constant from the tablet of core (11). Cross-sectional area (12) can be any geometry, as long as the region remains unchanged as core (11) dissolution.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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