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螺吲哚化合物及其作爲治療劑的應用
专利权人:
XENON PHARMACEUTICALS INC.
发明人:
MIKHAIL CHAFEEV,SULTAN CHOWDHURY,ROBERT FRASER,JIAN-MIN FU,RAJENDER KAMBOJ,DUANJIE HOU,SHIFENG LIU,MEHRAN SEID BAGHERZADEH,SERGUEI SVIRIDOV,SHAOYI SUN,JIANYU SUN,NAGASREE CHAKKA,TOM HSIEH,VANDNA RAINA
申请号:
HK15100208.1
公开号:
HK1199874A
申请日:
2015.01.08
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
This invention is directed to spiro-oxindole compounds of formula (I): wherein k, j, Q, R 1 , R 2a , R 2b , R 2c , R 2d , R 3a , R 3b , R 3c , and R 3d are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of preparing and using the compounds are also disclosed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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