VERWIJS, MARINUS JACOBUS,KARKARE, RADHIKA,MOORE, MICHAEL DOUGLAS
申请号：
CA2890106
公开号：
CA2890106A1
申请日:
2013.11.01
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Pharmaceutical compositions comprising 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5- yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1) in Form I and a solid dispersion comprising substantially amorphous N-(5-hydroxy-2,4-ditert-butyl-phenyl)-4- oxo-1H-quinoline-3-carboxamide (Compound 2), methods of treating, lessening the severity of, or symptomatically treating CFTR mediated diseases, such as cystic fibrosis, methods of manufacturing, methods of administering, and kits thereof are disclosed.
