The United States Government as Represented by the Department of Veterans Affairs;EMORY UNIVERSITY
发明人:
Philip Rather,David Weiss,Chui-Yoke Chin,Kyle Tipton
申请号：
US16647692
公开号：
US20200276293A1
申请日:
2018.09.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed herein is an attenuated Acinetobacter baumannii comprising an expression vector comprising a nucleic acid encoding the ABUW_1645 protein or a variant thereof. Disclosed herein are methods of treating or preventing colonization, infection, or disease by an Acinetobacter baumannii microbe, the method comprising administering a clinically effective dose of the attenuated Acinetobacter baumannii to a subject in need thereof, wherein the attenuated Acinetobacter baumannii comprises an expression vector expressing the ABUW_1645 protein or variants thereof.
