#$%^&*AU2015261555A120151217.pdf#####ABSTRACT Described is a method for injecting tissue without the use of a needle, using devices that include one or a combination of features such as a flexible shaft and an injection lumen along the shaft, and a control lumen, the distal end of the shaft comprising ejection orifices and at least one of the injection orifice are with non-normal angle relative to a central axis of the shaft comprising a fluid delivery system having an injector source wherein the shaft is capable of ejecting a fluid stream from the injection orifices, the fluid stream being capable of being injected into tissue by penetrating a tissue surface as a fluid stream and wherein the fluid injected from the first and second injection orifices produces an injection force on the distal end, and the distal end comprises at least one control orifice in communication with the control lumen from which control fluid can be ejected to produce a control force that opposes the injection force providing an injectate at the proximal end and in communication with the injection lumen placing the first and second injection orifices near a tissue surface without penetrating the tissue surface and pressurizing the injectate to cause the injectate to be ejected from the injection orifice as a fluid stream that passes through the tissue surface and disperses as fluid particles in tissue below the tissue surface.
