UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG;GOETHE UNIVERSITY
发明人:
ARBUTHNOT PATRICK,HEAN JUSTIN,ELY ABDULLAH,MARIMANI MUSA,BRZEZINSKA JOLANTA,DONOFRIO JENNIFER,BUFF MAXIMILIAN C. R.,ENGELS JOACHIM W.,BERNHARDT STEFAN
申请号：
IN3921CHN2014
公开号：
IN3921CHN2014A
申请日:
2014.05.23
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
This invention relates to modified short interfering RNA (siRNA) nucleic acid molecules particularly siRNA s which have been modified by the addition of a 2 0 guanidinopropyl (GP) modified nucleoside. In particular the invention relates to modified siRNAs which are capable of silencing target sequences methods of treating and preventing infection by using the siRNAs medicaments containing the siRNAs and use of the siRNAs.
