GOETHE-UNIVERSITY;UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG
发明人:
HEAN JUSTIN,ELY ABDULLAH,MARIMANI MUSA
申请号：
AP2014007650
公开号：
AP2014007650A0
申请日:
2012.10.26
申请国别(地区):
AP
年份:
2014
代理人:
摘要：
This invention relates to modified short interfering RNA (siRNA) nucleic acid molecules, particularly siRNA's which have been modified by the addition of a 2-0-guanidinopropyl (GP) modified nucleoside. In particular the invention relates to modified siRNAs which are capable of silencing target sequences, methods of treating and preventing infection by using the siRNAs, medicaments containing the siRNAs and use of the siRNAs.
