The present embodiments provide a medical device comprising a stent framework having proximal and distal regions and a lumen extending therebetween, and which comprises a biodegradable material. A first covering is coupled to at least a portion of an outer surface of the stent framework. When the stent framework is in an expanded deployed configuration, at least a portion of the first covering is disposed adjacent to a target site and fluid flows through the lumen of the stent framework. Further, the stent framework comprises a material that biodegrades a predetermined time after the first covering achieves at least partial remodeling at the target site. In various embodiments, one or more second coverings may be disposed adjacent to the first covering and comprise a material that biodegrades before the stent framework biodegrades.