Hadasit Medical Research Services & Development Limited
发明人:
申请号:
EP19191405.0
公开号:
EP3640326A1
申请日:
2008.04.27
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to a method of differentiating human pluripotent stem cells into retinal pigment epithelium (RPE) cells, the method comprising: a. culturing the human pluripotent stem cells in a medium supplemented with nicotinamide (NA) to generate differentiating cells; and thereafter b. culturing said differentiating cells in a culture system comprising one or more members of the TGF β superfamily, whereby said human pluripotent stem cells are induced to differentiate into RPE cells.