Hadasit Medical Research Services and Development Ltd.
发明人:
Benjamin Eithan REUBINOFF,Orna SINGER
申请号:
US15748541
公开号:
US20180216064A1
申请日:
2016.07.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method of generating retinal pigment epithelial (RPE) cells is disclosed. The method comprises: (a) culturing human pluripotent stem cells in a human feeder cell-conditioned medium to obtain a cultured population of human pluripotent stem cells; (b) culturing said cultured population of human pluripotent stem cells in a medium comprising a differentiating agent to obtain differentiating cells; and (c) culturing said differentiating cells in a medium comprising one or more members of the TGFβ superfamily.