The present invention provides a compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, which has an action of inhibiting an enzyme that produces 20-HETE. (In the above formula [I], the structure represented by the following formula [II] represents any of the structures represented by the following formula group [III]； R1, R2, R3, and R4 are independently , Hydrogen atom, fluorine atom, methyl and the like, and R5 represents any of the structures represented by the following formula group [IV]:本発明は、２０－ＨＥＴＥを産生する酵素を阻害する作用を有する下記式［Ｉ］で表される化合物又はその製薬学的に許容される塩を提供する。（上記式［Ｉ］中、下記式［ＩＩ］で表される構造は、下記式群［ＩＩＩ］で表される構造のいずれかを示し；Ｒ１、Ｒ２、Ｒ３、及びＲ４は、独立して、水素原子、フッ素原子、メチル等を示し、Ｒ５は、下記式群［ＩＶ］で表される構造のいずれかを示す：
