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ORAL DESINTEGRATION COMPRIMITE
专利权人:
TAKEDA PHARMACEUTICAL COMPANY LIMITED
发明人:
OKABE, TAKAYUKI,ISHII, SHIRO,EBISAWA, YUTAKA
申请号:
ECSP13012718
公开号:
ECSP13012718A
申请日:
2013.06.25
申请国别(地区):
EC
年份:
2013
代理人:
摘要:
An oral decay tablet obtained by the fine-grained compression method is provided, showing controlled release of lansoprazal and additives, 1. It can remove the broken fine particles in the process of compression, control the release of lansoprazal for treatment for a long time and effectively, and display the decay characteristics of oral decay tablets, including (I) display the released fine particles; Comment more than a month agoContaining fine particles containing active pharmaceutical ingredients and a coating of a copolymer of methacrylic acid / methyl acrylate / methyl methacrylate, Fine particles containing active pharmaceutical ingredients account for more than 80% by weight, not more than 300% by weight of copolymers, and (II) fine particles with controlled release of active pharmaceutical ingredients,Contains active pharmaceutical ingredients and coating, including (a) ethyl acrylate / methyl methacrylate and (b) one or more polymers selected from the group, composed of acrylic copolymer / ethyl acrylate, methyl phthalate, ethyl carbamate and ethyl acetate Cellulose FTA, in which the average particle size of fine particles (I) and fine particles (II) does not exceed 500 ml, and the active component of the drug is lansoprazal or one of its best active forms or salts.Se proporciona un comprimido de desintegración oral obtenido por compresión de gránulos finos que muestran una liberación controlada de lansoprazol y un aditivo, que es capaz de suprimir la rotura de los gránulos finos durante la compresión y puede controlar la liberación de lansoprazol terapéuticamente efectiva durante un tiempo prolongado y muestra una propiedad de desintegración en la cavidad oral.Un comprimido de desintegración oral que contiene (i) gránulos finos que muestran una liberación controlada de un ingrediente farmacéuticamente activo, que contiene gránulos finos con un ingrediente farmacéuticamente activo y una capa de recubrimiento con copolímero de ácido metacrílico/acrilato
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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