The present invention relates to an anticancer use of a novel compound, i.e., 2-methoxy-4-(3-(4-methoxyphenyl)propyl-1-en-1-yl)phenol. The compound of the present invention effectively inhibits the growth of cancer cells and tumors in vitro and in a xenograft animal model. The compound of the present invention shows an anticancer activity by inhibiting a DNA binding activity of transcription factor STAT 3 in cancer cells, inducing apoptosis of cancer cells, and reducing the expression of a cell cycle regulating protein. The compound of the present invention can be developed as an active ingredient of a strong anticancer drug.La présente invention concerne une utilisation anti-cancéreuse dun nouveau composé, à savoir le 2-méthoxy-4-(3-(4-méthoxyphényl)propyl-1-én-1-yl)phénol. Le composé selon la présente invention inhibe efficacement la croissance des cellules cancéreuses et des tumeurs in vitro et dans un modèle animal de xénogreffe. Le composé selon la présente invention présente une activité anticancéreuse par inhibition dune activité de liaison dADN du facteur de transcription STAT 3 dans des cellules cancéreuses, linduction de lapoptose de cellules cancéreuses, et la réduction de lexpression dune protéine de régulation du cycle cellulaire. Le composé selon la présente invention peut être développé en tant que principe actif dun médicament anticancéreux puissant.본 발명은 신규 화합물 2-메톡시-4-(3-(4-메톡시페닐)프로필-1-엔-1-일)페놀의 항암 용도에 관한 것이다. 본 발명의 화합물은 인 비트로 및 이종이식 동물모델에서 암세포와 종양의 성장을 효과적으로 억제한다. 본 발명의 화합물은 암세포에서 전사인자 STAT3의 DNA 결합 활성을 억제하고, 암세포의 세포사멸(apoptosis)를 유도하며, 세포주기 조절 단백질의 발현을 감소시킴으로써 항암 활성을 나타낸다. 본 발명의 화합물은 강력한 항암제의 활성성분으로 개발될 수 있다.
