The present invention relates to a drug delivery device for setting and dispensing a dose of a medicament, comprising: a body to accommodate a drive mechanism having a piston rod, a cartridge having a barrel sealed by a piston slidably displaced therein along an axial direction, wherein the cartridge is directly connectable with the body by way of an interface, and wherein the barrel comprises at least one radially extending portion at its outer periphery to cooperate with at least one further functional component of the device.
