The present invention discloses a process for the synthesis of herbal core shell titanium oxide quantum dots (QDs). By using graphene oxide as a initiator for synthesis of colloidal TiO2 nanoparticles and then herbal extract was used to synthesize one pot solvothermal method for photosensitive core-shell TiO2 quantum dots. These TiO2 quantum dots were tested against bacteria to study for its anti¬microbial effects with and without visible light. In most of the conditions tested, we observed a greater anti-bacterial effect of these TiO2 quantum dots whilst light activation as it gets more surface area with high photosensitivity. These herbal core shell QDs were characterized by using UV-Visible, Cyclic Voltametry, XRD, TEM and EDS analysis to confirm composition.