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COMBINATION OF SILOXAN AND AN ACTIVE INGREDIENT FOR TREATMENT OF DENTAL DISEASES
专利权人:
БАЙЕР ИННОВЕЙШН ГМБХ (DE)
发明人:
ШУЛЬЦ Ханс Х. (DE)
申请号:
RU2013107451/04
公开号:
RU2013107451A
申请日:
2011.07.13
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A pharmaceutical composition containing siloxane according to the general formula (I), in which R is —C — C-alkyl; R and R are each independently —C-C-alkyl, or together form a (2n) membered ring; and n is an integer from 2 to 8; for use in combination with a pharmacologically active ingredient for the prevention or treatment of a dental disease. 2. The composition according to claim 1, characterized in that R is —CH, R and R together form a (2n) membered ring, and n is an integer from 3 to 6.3. The composition according to claim 1, characterized in that the siloxane is octamethylcyclotetrasiloxane. The composition according to claim 1, characterized in that the use of the composition precedes, is carried out simultaneously and / or after the pharmacologically active ingredient. The composition according to claim 1, characterized in that the composition either contains a pharmacologically active ingredient in combination with siloxane according to the general formula (I), or the pharmacologically active ingredient is contained as a second, separate pharmaceutical composition. The composition according to claim 1, characterized in that the use of the composition and / or pharmacologically active ingredient is carried out locally and / or locally. The composition according to claim 1, characterized in that the use of the composition improves the penetration of the pharmacologically active ingredient into hard tissue. The composition according to claim 1, characterized in that the pharmacologically active ingredient is an antibiotic. The composition of claim 8, wherein the antibiotic is a gyrase inhibitor. The composition of claim 8, wherein the antibiotic is fluoroquinolone. 11. The composition of claim 8, wherein the antibiotic is selected from the group comprising doxycycline,1. Фармацевтическая композиция, содержащая силоксан, по общей формуле (I),,в которойR означает -C-С-алкил;Rи Rозначают каждый независимо друг от друга -C-С-алкил, или вместе образуют (2n)-чл
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