SON, HOE JOOKR,손회주,KIM, YOUNG TAEGKR,김영택,OH, DO YEONKR,오도연,JO, BONG SUNKR,조병선
申请号:
KR1020150027772
公开号:
KR1020160105557A
申请日:
2015.02.27
申请国别(地区):
KR
年份:
2016
代理人:
摘要:
The present invention relates to a refining method of olanzapine. In addition, the present invention provides a refining method for helpfully producing high purity olanzapine. The refining method of olanzapine comprises the steps of: a) obtaining olanzapine by crystallizing the olanzapine in a mixing solvent of methylene chloride and water b) separating the olanzapine by making the olanzapine react with base in the presence of water.COPYRIGHT KIPO 2016본 발명은 올란자핀의 정제방법에 관한 것이다. 본 발명은 고순도 올란자핀을 제조하는데 유용한 정제 방법을 제공한다.