THE JOHNS HOPKINS UNIVERSITY;TRUSTEES OF BOSTON UNIVERSITY
发明人:
BISHAI, WILLIAM R.,MURPHY, JOHN R.,CHEUNG, LAURENE,GUPTA, SHASHANK,BULLEN, CYNTHIA K.
申请号：
CA3017143
公开号：
CA3017143A1
申请日:
2017.03.10
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention is a DNA expression vector comprising: a toxP； a mutant toxO that blocks Fe-mediated regulation of gene expression； and a DNA sequence encoding a protein, wherein the toxP and the mutant toxO regulate expression of the DNA segment encoding the protein. It is preferred that DNA expression vectors of the present invention include DNA sequences encoding a signal peptide so that a protein expressed is attached to the signal peptide prior to processing. Novel proteins are produced off of the DNA expression vector of the present invention.
