UTILISATION DE LIGANDS CMH DE CLASSE II COMME ADJUVANTS POUR LA VACCINATION ET UTILISATION DE LAG-3 DANS LE TRAITEMENT DU CANCER

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专利权人:

MERCK SERONO SA;INSTITUT GUSTAVE ROUSSY

发明人:

TRIEBEL, FREDERIC

申请号：

CA2732570

公开号：

CA2732570C

申请日:

1998.07.23

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

The present invention concerns a use of a MHC class II ligand, such as CD4 and LAG-3, for the manufacture of a medicament for preventing or treating pathological conditions involving an antigen specific immune response, as well as the use of LAG-3 in cancer- immunotherapy. The invention also concerns a pharmaceutical composition comprising an effective amount of an antigen able to induce an antigen-specific immune response together with an effective amount of a MHC class II ligand wherein said MHC class II ligand is present as an adjuvant-like agent.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/