A subject of the invention is the compounds of formula (I):in which- either R1represents H, OH, NH2, -(CH2)m-NRaRb(m=0.1 or 2), Raand Rbrepresent H, linear, branched or cyclic (C1-C6) alkyl, (C3-C6) cycloalkyl-(C3-C6)-alkyl, Rc, S(O)2Rc, C(O)Rc, S(O)2Rdor C(O)Rdor Raand Rbwith N form an RcradicalRcrepresents a saturated, unsaturated or 5- or 6-members aromatic ring, containing 1 to 4 heteroatoms chosen from N, O and S, optionally substituted Rdrepresents a linear, branched or cyclic (C1-C6) alkyl, optionally substituted by 1 to 4 halogens or R1represents Rcor CHReRcor CHReRdRerepresents H, OH, NH2, NH-(C1-C6)-alk or N-(C1-C6)-alk2, or NH-(C1-C7)-acyl or NHRc R2represents H, (CH2)m-NRaRb, Rc, CHReRcor CHReRd,and R’2represents H it being understood that R1and R2cannot at the same time be H or that R1and R2or R2and R1cannot be one (CH2)m-NRaRbor Rcor H and the other one OH, or one H and the other one NH2, or one H and the other one (CH2)m-NRaRbin which Raand Rbrepresent H or alkyl or C(O)Rd, in which Rdrepresents an unsubstituted alkyl or cycloalkyl- or R1has the above definition except H and R2and R’2together represent gem dialkyl or alkyl-oxime, or R2and R’2represent respectively Rcor Rdand OH, NH2, NHRcor NHRf, Rfbeing a (C1-C7) acyl radical- or R1represents H and R2and R’2together represent alkyl-oxime or one represents Rcand the other one represents OH, NH2, NHRcor NHRf n is 0 or 1 R3and R’3represent H or (C1-C6) alkyl optionally substituted by 1 to 3 halogens or R3represents (C1-C6) alkoxy carbonyl and R’3represents H R4represents methyl optionally substituted by halogen R5represents H, (C1-C6) alkyl or (C7-C12) arylalkyl R6represents H, fluorine, NO2, CF3or CN in the form of enantiomers or mixtures, as well as their salts with acids and bases their preparation and their application as anti-bacterials, in both human and veterinary medicine.本發明提供一種式(I)化合物:其中,-一情形為:R1為H,OH,NH2,-(CH2)m-NRaRb(m為0,1或2);Ra及Rb為H,直鏈的、具有支鏈的、或環狀的(C1-C6)烷基,(C3-C6)環烷基-(C3-C6)-烷基,Rc,S(O)2Rc,C
