Use of Derivatives of piridopiridazina to treat cancer, autoimmune diseases, neurological and neurodegenerative and / or infectious and inflammatory diseases
Claim 1: The use of a compound characterized in that it is of the general formula (1) wherein the substituents R1, R2, X have the following meanings: X is O or S； R1: (I) unsubstituted or substituted aryl, where the aryl group may be substituted with one or more same or different substituents selected from F, Cl, Br, I, CF3, CN, NH2, NH-alkyl, NH-cycloalkyl, NH-heterocyclyl, NH-aryl, NH heteroaryl NH-alkyl-cycloalkyl, NH-alkyl-heterocyclyl NH-alkyl-aryl, NH-alkyl-heteroaryl, NH-alkyl-NH2, NH-alkyl-OH, N (alkyl) 2 , NHC (O) -alkyl, NHC (O) -cycloalkyl, NHC (O) -heterocyclyl, NHC (O) -aryl, NHC (O) -heteroaryl, NHC (O) -alkyl-aryl,NHC (O) -alkyl-heteroaryl, NHSO2-alkyl, NHSO2-cycloalkyl, NHSO2-heterocyclyl, NHSO2-aryl, NHSO2-heteroaryl, NHSO2-alkyl-aryl, NHSO2-alkyl-heteroaryl, NO2, SH, S-alkyl, S -aryl, S-heteroaryl, OH, OCF3, O-alkyl, O-cycloalkyl, O-heterocyclyl, O-aryl, O-heteroaryl, O-alkyl-cycloalkyl, O-alkyl-heterocyclyl, O-alkyl-aryl, O -alkyl-heteroaryl, O-alkyl-OH, O- (CH2) nO, O - (- CH2-CH2-O-) n-CH2-CH2-OH, OC (O) -alkyl, OC (O) -cycloalkyl , OC (O) -heterocyclyl, OC (O) -aryl, OC (O) -heteroaryl, OC (O) -alkyl-aryl, OC (O) -alkyl-heteroaryl, OC (O) -NH-alkyl, OSO3H , OSO2-alkyl, OSO2-cycloalkyl, OSO2-heterocyclyl, OSO2-aryl, OSO2-heteroaryl, OSO2-alkyl-aryl,OSO2-alkyl-heteroaryl, OP (O) (OH) 2, C (O) -alkyl, C (O) -aryl, C (O) -heteroaryl, O-CO2-alkyl, CO2H, CO2-alkyl, CO2- cycloalkyl, CO2-heterocyclyl, CO2-aryl, CO2-heteroaryl, CO2-alkyl-cycloalkyl, CO2-alkyl-heterocyclyl, CO2-alkyl-aryl, CO2-alkyl-heteroaryl, C (O) -NH2, C (O) NH -alkyl, C (O) NH-cycloalkyl, C (O) NH-heterocyclyl, C (O) NH-aryl, C (O) NH-heteroaryl, C (O) NH-alkyl-cycloalkyl, C (O) NH -alkyl-heterocyclyl, C (O) NH-alkyl-aryl, C (O) NH-alkyl-heteroaryl, C (O) N (alkyl) 2, C (O) N (cycloalkyl) 2, C (O) N (aryl) 2, C (O) N (heteroaryl) 2, SO-alkyl, SO-aryl, SO2-alkyl, SO2-heterocyclyl； SO2-aryl, SO2NH2, SO2NH-alkyl, SO2NH-aryl, SO2NH-heteroaryl, SO2NH-alkyl-aryl, SO3H,Soybean, asphalt, ni
