Pyrimidine derivative compound, its optical isomer, or a pharmaceutically acceptable salt thereof, and a composition for preventing or treating TYRO3-related diseases containing the same as an active ingredient
The present invention relates to a pyrimidine derivative compound, an optical isomer thereof, or a pharmaceutically acceptable salt thereof, and a composition for preventing or treating cancer containing the same as an active ingredient. Since the pyrimidine derivative compound, the optical isomer thereof, or a pharmaceutically acceptable salt thereof according to the present invention is excellent in the selective inhibitory effect against Tyro3 among TAM receptor inhibitory effects, it inhibits Axl and Mer. It can be used as an excellent composition for preventing or treating cancer without any side effects. [Selection diagram] Noneピリミジン誘導体化合物、その光学異性体、またはその薬学的に許容される塩、及びそれを有効成分として含むがん予防または治療用組成物に関する。本発明に係る前記ピリミジン誘導体化合物、その光学異性体、またはその薬学的に許容される塩は、TAM受容体阻害効果の中でも、特にTyro3に対する選択的阻害効果に優れるため、AxlおよびMerの阻害から現れる副作用なしに優れたがん予防または治療用組成物として使用できる。【選択図】なし