BENCSIK, JOSEF R,BLAKE, JAMES F,KALLAN, NICHOLAS C,MITCHELL, IAN S,SPENCER, KEITH LEE,XIAO, DENGMING,XU, RUI,CHABOT, CHRISTINE,DO, STEVEN,LIANG, JUN,SAFINA, BRIAN,ZHANG, BIRONG
申请号:
NZ58634609
公开号:
NZ586346A
申请日:
2009.01.09
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a 1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-l-yl)propan-1-one of Formula I and salts thereof, wherein: R1 is alkyl having one OH substitution R2 is hydrogen or F and R3 is Cl or CF3. Also disclosed is the use of said compound in the treatment of inflammatory, hyperproliferative, cardiovascular, neurodegenerative, gynecological or dermatological disease or disorder.