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methods for stabilizing tiotropium bromide micronized or ground solvates and preparing tiotropium bromide solvate, tiotropium bromide solvate, and use of stabilized solvates
专利权人:
ZENTIVA; K.S.
发明人:
Igor Cerna,Josef Hajicek,Mokhtar Kebbati,Ondrej Dammer,Pascal Billot,Patrick Hosek
申请号：
BR112015009654
公开号：
BR112015009654A2
申请日:
2012.11.05
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
1/1 summary â € œmethods for stabilizing microtized or milled tiotropium bromide solvates and preparing tiotropium bromide solvate, tiotropium bromide solvate, and use of Stabilized Solvates is a method for stabilizing micronized or milled tiotropium bromide solvates, wherein the solvates are deposited in a saturated atmosphere of the appropriate solvent for a period sufficient for recovery. that of the original amount of solvent in the solvate. a stable tiotropium bromide solvate with 1,3-propanediol.1 / 1 resumo “mã‰todos para a estabilizaã‡ãƒo de solvatos micronizados ou moã�dos de brometo de tiotrã“pio e preparar o solvato de brometo de tiotrã“pio, solvato de brometo de tiotrã“pio, e, uso de solvatos estabilizadosâ€� um mã©todo para estabilizaã§ã£o de solvatos micronizados ou moãdos de brometo de tiotrã³pio, em que os solvatos sã£o depositados em uma atmosfera saturada do solvente adequado durante o perãodo de tempo suficiente para recuperaã§ã£o da quantidade original de solvente no solvato. um solvato de brometo de tiotrã³pio estã¡vel com 1,3-propanodiol.
来源网站：
中国工程科技知识中心
来源网址：
http://www.ckcest.cn/home/
