The present invention concerns a syringe (1) for drug infusion to a patient, the syringe being of a kind that can be used in combination with a drug infusion device (10) and can be coupled to said device through a rotary movement. According to the invention, the syringe (1) has at least one stop tooth (9) for limiting the rotation of said syringe (1) relative to said infusion device (10), thereby preventing any further rotation of the syringe (1) once it has been properly coupled with the infusion device (10) and thus avoiding the risk of disconnecting said syringe from said device. The present invention further concerns a drug infusion device (10) incorporating such a syringe (1).
