Marianne BRUGGEMANN,Roland BUELOW,Michael J. OSBORN,Biao MA
申请号:
US14517755
公开号:
US20150113668A1
申请日:
2014.10.17
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to polynucleotides, particularly chimeric polynucleotides useful for optimal production of functional immunoglobulins with human idiotypes in rodents. The invention further relates to rodents comprising such polynucleotides.