An endoscope system includes an endoscope objective optical system that acquires two optical images with different focus positions two image pickup devices that receive and photoelectrically convert the two optical images an image synthesis processing section that synthesizes two images corresponding to the two optical images photoelectrically converted by the two image pickup devices into one image and a focus switchover mechanism that moves a position of a focus switchover lens provided for the endoscope objective optical system and selectively switches a focus of the endoscope objective optical system to one of two observation regions of proximity observation and remote observation, in which the image synthesis processing section synthesizes the two images in each of the respective observation regions of the proximity observation and the remote observation.