ANDREWS STEVEN W,BLAKE JAMES F,CHICARELLI MARK J,GOLOS ADAM,HAAS JULIA,JIANG YUTONG,KOLAKOWSKI GABRIELLE R
申请号：
IN201837004852
公开号：
IN201837004852A
申请日:
2018.02.08
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X 1 , X 2 , X 3 and X 4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
