TANG, MIN,SHAN, JOSEPH S.,KING, STEVEN W.,CHANG, CONNIE,BROWN, MICHAEL A.
申请号:
CA3037008
公开号:
CA3037008A1
申请日:
2017.09.26
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Disclosed are surprising new methods and kits for identifying and treating patients treatable with PS-targeting antibodies, particularly for identifying and treating cancer patients using bavituximab and bavituximab combination therapies. The methods and kits are based on the surprising finding that defined ranges of pre-treatment blood concentrations of ß2-glycoprotein 1 (ß2G??), particularly functional ß2GPI, act as an indicator to accurately predict patients with better treatment outcomes.