MENET CHRISTEL JEANNE MARIE,HODGES ALASTAIR JAMES,VATER HUW DAVID
申请号：
IN2025/MUMNP/2013
公开号：
IN2013MN02025A
申请日:
2013.10.30
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
A pyrazolopyridine compound according to Formula I able to inhibit JAK is disclosed as well as pharmaceutically acceptable salts a solvate thereof solvates of the pharmaceutically acceptable salts and biologically active metabolite thereof. The compound may be prepared as a pharmaceutical composition and may be used for the treatment or prophylaxis of a variety of conditions in mammals including humans and particularly such conditions as may be associated with aberrant JAK activity including by way of non limiting example allergy inflammatory conditions autoimmune diseases proliferative diseases transplant rejection diseases involving impairment of cartilage turnover congenital cartilage malformations and/or diseases associated with hyper secretion of IL6.
