PROBLEM TO BE SOLVED: To provide novel means by which high storage stability of a rosuvastatin calcium tablet, a hypercholesterolemia therapeutic agent, is shown.SOLUTION: The invention provides a tablet in which high storage stability is shown by inhibiting the production of impurities, such as a lactone body, in an environment with high heat and humidity, the tablet containing rosuvastatin calcium represented by the following formula a stabilizer selected from D-mannitol, hydrous silicon dioxide, L-arginine, sodium carbonate, and tetrasodium pyrophosphate and a disintegrant selected from crospovidone, low substituted hydroxypropylcellulose, corn starch, and partial pregelatinized starch.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】高コレステロール血症治療薬のロスバスタチンカルシウム錠剤の高い貯蔵安定性を示す新たな手段の提供。【解決手段】下式で表されるロスバスタチンカルシウムに、D-マンニトール、含水二酸化ケイ素、L-アルギニン、炭酸ナトリウム、及びピロリン酸四ナトリウムから選ばれる安定化剤、及びクロスポビドン、低置換度ヒドロキシプロピルセルロース、トウモロコシデンプン、及び部分α化デンプンから選ばれる崩壊剤を含有する、熱及び湿度が高い環境において、ラクトン体等の不純物の生成を抑制し、高い貯蔵安定性を示す錠剤。【選択図】なし