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Solid forms comprising 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one, and a coformer, compositions and methods of use thereof
专利权人:
SIGNAL PHARMACEUTICALS LLC
发明人:
KLOPFER KEVIN
申请号:
NZ62988414
公开号:
NZ629884A
申请日:
2014.09.03
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Provided herein are solid forms comprising 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one and a coformer such as fumaric acid, benzoic acid, gentisic acid or maleic acid. Pharmaceutical compositions comprising such solid forms (e.g., cocrystals) and methods of use for treating, preventing, and managing various disorders are also provided herein, particularly with regard to reducing tumour load in cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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