PROBLEM TO BE SOLVED: To provide a pharmaceutical composition in which an interaction between loxoprofen or a salt thereof and an interactive component is suppressed. SOLUTION: The following components (A), (B) and (C): (A) Loxoprofen or its salt (B) Lemon oil (C) A pharmaceutical composition containing a silicic acid compound. [Selection diagram] None【課題】ロキソプロフェン又はその塩と、相互作用性成分との間の相互作用が抑制された医薬組成物の提供。【解決手段】次の成分(A)、(B)及び(C):(A)ロキソプロフェン又はその塩(B)レモン油(C)ケイ酸化合物を含有する医薬組成物。【選択図】なし