University of North Texas Health Science Center at Fort Worth
发明人:
CISTOLA, David P.,ROBINSON, Michelle D.
申请号：
EP16747398
公开号：
EP3253287A4
申请日:
2016.02.06
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The subject invention pertains to a method that involves at least three steps: (1) acquisition of a NMR data set or spin relaxation curve for plasma, serum or whole blood samples, or for tissues monitored from outside the body, (2) analysis of the NMR data or relaxation curve to extract the T2 and/or T1 relaxation times for water (or surrogates thereof), and (3) conversion of the water T2 and/or T1 values (or surrogates thereof) into a measure of someone's health status (referred to as a T2 or T1 health score depending on the value (T1 or T2 or both T1 and T2) associated with the score). The T1 and/or T2 health score utilizes a statistical database derived from previous studies of subjects ranging from normal, healthy individuals to those having varying degrees of hidden or non-hidden metabolic abnormalities, such as inflammation, insulin resistance, lipid abnormalities (dyslipidemia), oxidative stress, brain abnormalities, cognitive impairment or other disorders, and provides a measure of a subject's overall metabolic and brain health status.
