The invention relates to a compound of the general formula (I) or a physiologically functional derivative, solvate or salt thereof, (I) wherein A is a bond, alkyl or alkoxy optionally substituted with one or more R&rdquo； as defined herein, *-N(R&rdquo；&rsquo；)CO-, *-CON(R&rdquo；&rsquo；)-, *-N(R&rsquo；&rdquo；)CON(R&rdquo；&rsquo；)-, -S-, -SO-, *-N(R&rsquo；&rdquo；)-, *-N(R&rsquo；&rdquo；)CO-, *-CON(R&rsquo；&rdquo；)-, -CO-, *-COO-, *-OOC-, *-S02N(R&rdquo；&rsquo；)-, -S02, or *-N(R&rdquo；&rsquo；)-SO2-, wherein R&rdquo；&rsquo； is as defined herein and * specifies the point of attachment to X； X is aryl, cycloalkyl, aralkyl, heterocyclyl or heteroaryl, which may be substituted with one or more Rx further described herein； L is a bond or *-N(RN)CO-, *-CON(RN)-, *-N(RN)-, *-C=N(RN)-, *-N(RN)-alkyI-, *-alkyl-N(RN)-, *-N(RN)CON(RN)-, *-CO-, *-S02-, alkyl, *-alkyl-0-alkyl-, *-NCO-CH=CH-, *-CH=CH-CONH-, * -S02N(RN)-, *-N(RN)S02-, or heterocyclyl, wherein * specifies the point of attachment to X； Y is H, alkyl, aryl, aralkyl, cycloalkyl, heterocyclyl or heteroaryl, which may be substituted with one or more RY further described herein； and R and RN are further described herein； as well as their use as a medicament, a pharmaceutical composition comprising them, a method of treatment or prevention of a medical condition entailing the administration thereof, and the use thereof in the manufacture of a medicament for the treatment or prevention of a medical condition, particularly autoimmune inflammatory disorders, CNS disorders, sleeping disorders, or proliferative diseases including cancer. The invention further relates to a specific process for the preparation of said compounds.
