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Bifluorodioxalane-amino-benzimidazole kinase inhibitors for the treatment of cancer, autoimmuneinflammation and CNS disorders
专利权人:
4SC DISCOVERY GMBH
发明人:
Johann Leban,Mirko Zaja
申请号:
US14411795
公开号:
US09580438B2
申请日:
2013.06.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to a compound of the general formula (I) or a physiologically functional derivative, solvate or salt thereof,whereinA, X, L, Y, R, and RN are as defined herein. The invention further relates to the use of the compounds of formula (I) as a medicament, a pharmaceutical composition comprising them, a method of treatment or prevention of a medical condition entailing the administration thereof, and the use thereof in the manufacture of a medicament for the treatment or prevention of a medical condition, particularly autoimmune inflammatory disorders, CNS disorders, sleeping disorders, or proliferative diseases including cancer. The invention further relates to a specific process for the preparation of said compounds.
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