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DISPERSION SOLIDE AMORPHE COMPRENANT UN TAXANE, COMPRIMÉ CONTENANT LA DISPERSION, ET MÉTHODE DE PRÉPARATION ASSOCIÉE
专利权人:
Hanmi Pharm. Co.; Ltd.
发明人:
申请号:
EP15773354.4
公开号:
EP3125872B1
申请日:
2015.03.20
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Provided is an amorphous solid dispersion including a taxane or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable polymer, and a pharmaceutically acceptable surfactant, which has enhanced solubility. Also provided is a method for preparing the solid dispersion. The present subject matter also provides a tablet having good solubility, bioavailability and stability, which comprises the amorphous solid dispersion, an intragranular excipient, and an extragranular excipient.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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