SRINIVASAN, SHANMUGAM,IM, HO TAEK,YOON, YOUNG SU,KIM, YONG IL,PARK, JAE HYUN,WOO, JONG SOO
申请号：
CA2944438
公开号：
CA2944438A1
申请日:
2015.03.20
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention provides an amorphous solid dispersion comprising a taxane or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable polymer, and a pharmaceutically acceptable surfactant, which has enhanced solubility. Also provided is a method for preparing the solid dispersion. The present invention also provides a tablet having good solubility, bioavailability and stability, which comprises the amorphous solid dispersion, an intragranular excipient, and an extragranular excipient.
