An image pickup device includes: an image pickup element a spacer surrounding a light receiving surface of the image pickup element a cover glass attached to the spacer, the cover glass being disposed opposing to the light receiving surface and an insulative resin configured to thermally couple the image pickup element with the cover glass, and to have a thermal conductivity of not less than 8 W/mK. An endoscope includes: the image pickup device an image pickup optical system a drive circuit a light guide configured to radiate light from a illumination light source a tubular body configured to accommodate the image pickup device, the image pickup optical system, the drive circuit, the light guide, and a forceps opening and a first insulative resin having a thermal conductivity of not less than 8 W/mK, and adapted to thermally couple the image pickup device with the drive circuit.