An image pickup device (100) comprises an image pickup element (102), a spacer (106) surrounding a light receiving surface of the image pickup element, a cover glass (108) attached to the spacer opposite the light receiving surface, and an insulative resin (112) configured to thermally couple the image pickup element with the cover glass. The insulative resin has a thermal conductivity of not less than 8 W/mK.The image pickup device can be used in an endoscope (10) which also includes an image pickup optical system (50), a drive circuit (80), a light guide (90), a forceps opening (56) and a tubular body (66) for accommodating these parts. A second insulative resin (116) having a thermal conductivity of not less than 8 W/mK, can thermally couple the image pickup device with the drive circuit.