The invention relates to a lotus seedpod extract (LSE) and its use for improving atherosclerosis by applying an effective does of the LSE to an individual required for improving the symptoms of atherosclerosis. The LSE is manufactured by steps of preparing a lotus material extracting the lotus material by a hot water to obtain a solution filtering the solution to obtain a filtrate and finally dehydrating the filtrate to obtain a LSE rich in flavonoids.本發明係有關於一種蓮蓬萃取物及其改善動脈粥狀硬化(atherosclerosis)之用途,其係將一有效劑量之蓮蓬萃取物投予一所需個體,以改善動脈粥狀硬化症狀,其中蓮蓬萃取物係以下列步驟製得:提供一蓮蓬材料,利用熱水萃取蓮蓬材料以獲得一溶液,再經由過濾以獲得一濾液,最後乾燥濾液以製得一富含類黃酮(flavonoid)之蓮蓬萃取物。
