The invention is a single use intradermal injection device capable of intradermal delivery an agent (e.g., vaccine, drug, medicament, etc.) in a controlled manner and without requiring specialized skill in administering delivery of such agent. The injection device is configured to be filled on-site and in the field with a microdose of an agent, while remaining sterile and preventing the potential for contamination during the filling process. The injection device is further configured to be rendered incapable of reuse following its delivery of the agent to a patient, thereby preventing reuse of the device and reducing the risk of the spreading blood- borne diseases through reuse.