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脈管の傷害後の再狭窄を防ぐためのラパマイシンとの組み合わせにおけるトポテカンの局所的脈管配給
专利权人:
コーディス・コーポレイション
发明人:
ロバート・ファロティコ,トム・ジェイ・ペリー,ジョナサン・ゼット・ザオ
申请号:
JP2005064217
公开号:
JP5042458B2
申请日:
2005.03.08
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organisms reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organisms reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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