Fionn Hurley,Steven R. Johnson,Thomas Ciaran Loughman,Zheng Xin Dong
申请号：
BRPI0918993
公开号：
BRPI0918993A2
申请日:
2009.09.22
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The present invention relates to a process for the large-scale synthesis of (Aib8,35)hGLP-1(7-36)-NH2 (SEQ ED NO:2), i.e., His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gb-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Aib-Arg-NH2 (SEQ ID NO:2), which comprises solid-phase Fmoc-chemistry.
