Non-ionic, low osmolar contrast agents for delivery of antisense oligonucleotides and treatment of disease

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专利权人:

The Ohio State Innovation Foundation

发明人:

Burghes, Arthur,Porensky, Paul,Kaspar, Brian

申请号：

AU2012347765

公开号：

AU2012347765A1

申请日:

2012.12.06

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

Disclosed are compositions comprising an antisense oligonucleotide and a non-ionic, low-osmolar contrast agent. Also disclosed are methods of delivering an antisense oligonucleotide to a target sire comprising incorporating the antisense oligonucleotide into a composition comprising a non-ionic, low-osmolar contrast agent. Also disclosed are methods of treating a neurodegenerative disease comprising administering one or more of the compositions disclosed herein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/