Stable compositions comprising tirofiban hydrochloride and a method for the preparation thereof

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专利权人:

GLAND PHARMA LTD

发明人:

SURAPANINI SRIDEVI DR,DR SURAPANINI SRIDEVI,GOLLAGUNTA NADAMUNI DR,DR GOLLAGUNTA NADAMUNI,CHAVA ARAVINDA,CHAVA ARAVINDA,POTTURI ARUN KUMAR,POTTURI ARUN KUMAR,PILLA RAMARAO,PILLA RAMARAO,GANDETI CHANDR

申请号：

IN931/CHE/2013

公开号：

IN2013CH00931A

申请日:

2013.03.04

申请国别(地区):

IN

年份:

2015

代理人:

摘要：

A stable composition comprising 2-S-(n-Butylsulfonylamino)-3-[4-(4-(piperidin-4-yl)butyloxy)phenyl]propionic acid monohydrochloride monohydrate (Tirofiban hydrochloride) as active pharmaceutical ingredient and method for the preparation is disclosed. The composition exhibits an improved chromatographic profile and greater stability with respect to the particulate matter.

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