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DUAL MODULATORS OF 5-HT2A AND D3 RECEPTORS
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
GOBBI, LUCA,路卡 高毕,路卡 高畢,JAESCHKE, GEORG,乔治 杰许柯,喬治 傑許柯,ROCHE, OLIVIER,奥利佛 罗契,奧利佛 羅契,SARMIENTO, ROSA MARIA RODRIGUEZ,罗沙 玛莉亚 罗瑞格 沙米恩托,羅沙 瑪莉亞 羅瑞格 沙米恩托,STEWARD, LUCINDA,鲁辛达 史都华,魯辛達 史都華
申请号:
TW097128485
公开号:
TWI363623B
申请日:
2008.07.25
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The bright Department Off whats of this Hair are used as thrombocytin 5-HT2a With dopamines (dopamine) D3 by the compound of the logical formula (I) of the Twin Tone Festival Elixirs of Body:Wherein R1, R2, X and n Department Ding Righteousness as illustrated Books Zhong SuoIts System makes, closes object containing its Medical Drug Group and its makees the purposes of As Medical Drug product. Compound Right dopamine Ds 3 With thrombocytin (the 5- Hydroxyalkyl tryptamines of logical formula (I)5-HT) 5-HT2A Shou Body Ju You Gao Pro and power and can effectively control Treatment Jing Shen Shi Tone diseases and other diseases , Zhu such as Yi Yu diseases Ji Jiao Account diseases, Drug objects according to Lai Zheng, Crazy stay disease and note Yi Zhang Hinder.本發明係關於用作血清素5-HT2a與多巴胺(dopamine)D3受體之雙調節劑的通式(I)之化合物:其中R1、R2、X及n係如說明書中所定義;其製造、含有其之醫藥組合物及其作為醫藥品之用途。通式(I)之化合物對多巴胺D3與血清素(5-羥色胺;5-HT)5-HT2A受體具有高親和力且可有效治療精神失調症以及其他疾病,諸如抑鬱症及焦慮症、藥物依賴症、癡呆症及記憶障礙。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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